National Institute for Health and Clinical Excellence (NICE)
NICE is an independent organization responsible for providing national guidance on promoting good health and preventing and treating ill health in England and Wales in the United Kingdom. NICE makes recommendations to the NHS on new/ existing medicines, treatments and procedures, and treating and caring for people with specific diseases and conditions. NICE makes recommendations to the NHS, local authorities and other organizations in the public, private, voluntary and community sectors on how to improve people's health and prevent illness and disease.
Clinical practice guidelines: http://guidance.nice.org.uk/Scottish Intercollegiate Guidelines Network (SIGN)
SIGN develops evidence based clinical practice guidelines for the National Health Service (NHS) in Scotland. Guidelines are derived from a systematic review of the scientific literature and are designed as a vehicle for accelerating the translation of new knowledge into action to meet their aim of reducing variations in practice, and improving patient-important outcomes.
Clinical practice guidelines: http://www.sign.ac.uk/guidelines/index.html